There is concern recently about the Autorun feature using CD-ROM's on your computer.

What is Auto Run, Auto Play? When an Autorun-enabled CD-ROM is inserted into a CD-ROM drive, Windows automatically launches the program contained on the disk, whether you want it to or not.

Due to increasing threats from the Conficker-Downadup Worm and other malware, US-CERT strongly recommends that Autorun/Autoplay be disabled on all computers.